Aurelia Probiotic Skincare Ltd - Organic Skin Care

Explaining the Science - Q&A | Aurelia Probiotic Skincare. Discover the power of probiotics.

Explaining The Science

Discover more about your skin, the challenges it faces as we age and how you can help to slow this process down. Our Science Q&A will help you to understand more about the science behind your skin and how Aurelia Probiotic Skincare really works to combat signs of ageing.

WHY OUR SKIN AGES

 

The root cause of premature skin ageing is excessive cellular inflammation which upsets the natural and delicate balance of our skin’s immune system. We all suffer from cellular inflammation, particularly as we age and it is associated with factors such as lack of sleep, hormones, emotional stress, as well as excessive sunlight, harsh weather conditions, air pollutants and cigarette smoke.


IN MORE DETAIL

While being a vital defence mechanism, excessive inflammation has been proven to cause premature ageing and occurs as a result of internal mechanisms such as the by-products of cellular metabolism and external factors such as high levels of UV radiation. Inflammation is characterised by a number of events which occur including increased blood flow, migration of immune cells, and release of free radicals and damage to normal tissue. Aurelia Probiotic Skincare helps to manage the level of inflammation within the skin, the main cause of ageing.



How does my skin naturally regulate inflammation?

 

The body uses molecules called cytokines to naturally regulate inflammatory responses. Cytokines are a group of molecules that work within the skin's defence system and are important for cell communication. They are released by some cells and affect the behaviour of other cells. They are particularly important in health and disease, specifically in responses to infection, trauma and inflammation.


IN MORE DETAIL

It is important for these immune responses to be regulated, ensuring the skin isn't in a persistent state of inflammation, which can create an environment that accelerates the ageing process. Today's stressful lifestyles, alongside UV damage and external aggressors, facilitate this cycle of inflammation. Cytokines stimulate or inhibit cellular activities and play a key role in helping to control the inflammatory process and the repair of damaged skin. When the skin is not inflamed and is in a balanced and protected state DNA repair is optimised. For example, cytokine Interleukin 10 (IL10) would signal to white blood cells creating an immune response once inflammation is detected. This response is then regulated back and forth to stimulate or suppress the inflammatory response when required – achieving moderation and therefore the perfect balance.



When will my skin begin ageing?

 

The rate and stage at which we age depends on a number of factors including genetics, lifestyle, exposure to UV light and exposure to environmental stressors and internal factors such as stress and hormones. However, first signs of ageing usually occur in our mid to late 20s or early 30s, with fine lines appearing, pigmentation, a change in skin texture and loss of skin radiance resulting in dullness. Aurelia Probiotic Skincare's Age Prevention range has been specifically designed to target these early skin changes and continues to help manage the levels of inflammation within the skin as we age.



How does inflammation impact the skin’s extracellular matrix?

 

When skin is under stress and inflammation occurs, the extracellular matrix’s (ECM) function deteriorates. The ECM is essential for processes like growth and skin healing. When the skin becomes inflamed at the cell layer, degradation of the ECM occurs and it can no longer maintain the skin’s firm and elastic structure, leading to premature ageing.


IN MORE DETAIL

The ECM is the non-cellular component present within all tissues and organs and it has many important functions: it surrounds and supports cells, influences cell shape and movement and regulates cellular functions through signalling. It consists of fibres (e.g. collagen and elastin), proteoglycans and polysaccharides (e.g. hyaluronic acid) which provide a voluminous hydrated matrix and adhesive glycoproteins (e.g. fibronectin) which connect cells with fibres.



Why does my skin become dull and fatigued with age?

 

As we become older one of the main indications of ageing is when our skin starts to lose its natural glow and begins to look dull and tired. When young, our body’s renewal processes behave optimally and our skin cells turn over on average every 28 days. As we age the body’s natural ability for cell renewal deteriorates. Although the rest of our body may feel energised, the blood flow to our skin and the body’s natural replenishment process slows down and the skin’s natural enzymes that help remove and replace dead cells become inefficient. This can lead to dead skin cells piling up, which absorb light and cause our skin to appear dull and fatigued.

Dullness is a major ageing skincare concern and one we focus on greatly improving at Aurelia Probiotic Skincare.



Why do I get wrinkles?

 

Smooth, plump skin relies on proteins called collagen and elastin. When these two proteins are compromised, wrinkles become visible. Collagen, together with elastin, is responsible for skin strength and elasticity and these proteins give skin its youthful, supple and toned appearance. Collagen strands within the Extracellular Matrix (ECM) help to hold the skin’s structure together and form the framework of tissues. As we age, and degradation occurs, these collagen strands slacken and can break, which causes the skin to sag and wrinkles to form.

 


IN MORE DETAIL

Damage caused by inflammation and free radical formation also triggers the release of collagen- and elastin-digesting enzymes, which cause their degradation, a key factor in the loss of skin tone, skin sagging and wrinkles. In particular, fine lines and wrinkles around the eyes are also explained by the reduced effectiveness of the proteasomes within our skin cells. Proteasomes are found within our cells and their role is to destroy other proteins. They are involved in many essential cellular functions, such as regulation of the cell cycle, signalling and processing for appropriate immune responses and inflammatory responses - it is complicated and multifaceted. Strengthening the proteasome improves the natural recycling process in skin cells which helps to delay skin ageing. As we get older our proteasomes becomes less effective and this leads to the formation of fine lines and wrinkles. These often begin around the eyes and mouth.



WHY DO I GET PIGMENTATION?

 

With age, our skin becomes more prone to the development of pigment spots, a hallmark of photo-exposed skin.

Normally appearing on our face neck and hands, these clusters of excess pigment (melanin) are typically the combined result of prolonged sun exposure and high levels of stress in our skin cells.

This is because prolonged UV exposure and intense stress in our skin cells can trigger biological pathways that lead to overproduction of melanin in clusters of cells. This excess melanin is transported from melanin producing skin cells to cells in upper layers of the skin, where the dark brown spots form.



What role do free radicals play in causing our skin to age?

 

The knock on effect of this damage to the skin can also trigger the release of collagen and elastin-digesting enzymes. Collagen and elastin are important proteins which are responsible for skin strength and elasticity. They give skin its youthful supple and toned appearance and their degradation (caused by the harmful enzymes) leads to loss of skin tone, skin sagging and wrinkles.

Free radicals can cause damage to healthy cells by a process called oxidative stress which occurs in the following way:



Creates unstable molecules

Free radicals are molecules that have lost an electron which leaves them ‘incomplete’ and less stable. The free radical wants to replace its missing electron to become ‘complete’ again and is therefore more reactive than when it had all of its electrons.



Steals a healthy cell’s electrons

One way for the free radical to gain an electron and become ‘complete’ again is to react with a healthy cell molecule and ‘steal’ one of its electrons. This re-balancing process however damages the healthy cell molecule - losing one of its electrons can affect its function. When the healthy cell is attacked by the free radical and has one of its electrons stolen it then becomes a free radical itself.



Cellular DNA becomes damaged

The cell is now an unstable free radical and attempts to steal an electron from another neighbouring ‘complete’ and healthy cell. This causes a chain reaction to start in which many healthy cells may have their electrons ‘stolen’ from free radicals. The free radicals may react with important cellular components such as DNA or the cell membrane and cause irreparable damage to the cell or cause the cell to die. This contributes significantly to the ageing process as once the process has started, it can cascade, resulting in oxidative stress, damage to the skin structure and excessive levels inflammation within our skin.



What can be done to counteract free radicals?

 

A healthy antioxidant rich diet, using sun protection, relaxing more, limiting stress and drinking lots of water is a start. Using great skincare helps too! Aurelia Probiotic Technology works to harness this free radical damage, oxidative stress and systematic inflammation by using antioxidants throughout its products - this is the first fundamental step towards helping to fight ageing.


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How do antioxidants help prevent skin damage?

 

Antioxidants are naturally found in abundance in plants and fruit. Using antioxidant rich skincare is a great way to treat your skin and is the first step in helping to prevent ageing.

Antioxidants are substances which can prevent or slow cell damage in the following way:

Stabilise Cells Preventing Cell Damage An antioxidant gives one of its own electrons to an ‘incomplete’ and unstable free radical who is missing an electron. By receiving an electron from an antioxidant and becoming ‘complete’ again, the free radical does not need to steal one from a healthy neighbouring cell, resulting in the prevention of cell damage.



Thousands of natural antioxidants are found in fruit, vegetables and plants and include vitamins A, C, and E. Aurelia Probiotic Skincare is abundant in natural antioxidants from the precious BioOrganic botanicals used throughout the range that are ethically sourced from around the world. The high antioxidant content combats free radicals which are the cause oxidative stress, damage to the skin structure and, at excessive levels, induce an inflammatory response. They terminate chain reactions by removing free radical intermediates and inhibit other oxidation reactions. They do this by being oxidised themselves, working to reduce free radicals and prevent skin ageing.

Aurelia Probiotic Skincare has been all over the world and searched for the very best BioOrganic botanicals which are rich in antioxidants to add to our scientifically developed formulations. Antioxidants are fantastic when dealing with the first signs of skin ageing and paired with our three technologies offer revolutionary, next generation age prevention.

To learn more about our antioxidant rich BioOrganic botanicals, read the A-Z of ingredients and watch our botanical research film made in Malawi.



Helping to prevent our skin from ageing

Aurelia Probiotic Skincare continually seeks scientific excellence by pushing the boundaries of skincare. We are passionate about providing women with revolutionary, next generation probiotic technology combined with ethically sourced 100% BioOrganic botanical formulations. Aurelia Probiotic Skincare prides itself on its beautiful mix of science, nature and luxury. We offer women age prevention beyond just antioxidants and invite women to discover the power of probiotics.

 

What are probiotics?

 

Probiotics are live or non-live bacteria and are commonly available in foods, supplements and now skincare. “Pro” means “for” or “in favour of,” and “biotic” means “life.” Therefore, probiotic means “for/in favour of life’. Many are familiar with the benefits of probiotics using them in their day to day life. Aurelia Probiotic Skincare are using next generation technology making probiotics widely accessible in skincare offering abundant benefits.



How are probiotics used in Aurelia Probiotic skincare?

 

Our probiotic is used in the form of a glycoprotein from bifido bacteria designed to balance stress-damaged skin and stabilise the skin's defence system to ensure the skin is optimally responsive. Aurelia Probiotic Skincare’s glycoproteins are responsible for regulating the skin’s immune response to regain and achieve natural balance. This active lowers the stress level in the skin, protects it against the environmental stresses and stabilises the immune system. It generates targeted responses through reduction or activation within the skin, depending on what is needed. By supporting the right balance of these cytokines (helping to moderate), Aurelia Probiotic Skincare promotes the natural repair process and helps to counteract the signs of premature ageing.


What is a Glycoprotein?

Glycoproteins are cell surface molecules which enable communication between the vast numbers of cells within our bodies; they are essential for cell-to-cell communication. They allow our cells to send and translate messages to each other, enabling them to communicate clearly and operate efficiently. They help to nourish, control, protect and support our skin cells and without them, our skin could not function optimally.



How does Aurelia’s Probiotic Technology work?

 

Our Probiotic Technology protects and balances the skin by acting against immune system imbalances in our skin cells that can occur as a result of stresses such as UV exposure. These imbalances involve cytokines IL-10 and IL-12*, key messenger molecules in our skin’s immune system.

By maintaining a healthy balance between these molecules we can boost our skin’s natural defence system leaving our skin less prone to stress. Protecting the skin from environmental stresses and cellular inflammation increases the resilience of our skin cells and counteracts the signs of premature ageing.

This is our core approach to providing anti-ageing care that restores and maintains balanced, healthy and glowing skin.


IN MORE DETAIL

Cytokines are the body's natural immune regulators and they are very important signalling molecules that communicate to our body to activate or suppress an inflammatory response. Aurelia Probiotic Skincare's probiotic technology and repair complex works in synergy, protecting the skin against excessive levels of IL-10* cytokines which are produced in response to stresses such as excessive exposure to UV light. IL-10 suppresses our skin's immune system and this includes the suppression of other cytokines, such as IL-12* which have been shown to be involved in the repair and control of UV-induced DNA damage. By supporting the right balance of these cytokines, Aurelia Probiotic Skincare helps to control the level of inflammation within our skin and counteracts the signs of premature ageing.

*Interleukin 10 (IL-10) & Interleukin 12 (IL-12)



How does Aurelia’s Repair Complex work?

 

Aurelia’s Repair complex acts against environmental stresses, such as excessive sun exposure that can upset the natural and delicate balance of the skin’s immune system and challenge the skin’s ability to repair itself.

Working in synergy with the Probiotic complex, Aurelia’s Repair complex targets immune system imbalances in our skin cells involving cytokines (IL-10 and IL-12*), which are the body's natural immune regulators and have important roles in controlling and repairing DNA damage that can be caused by UV exposure.

By rebalancing the proportion of these cytokine mediators in the skin, ARC increases natural DNA repair by up to 40% and protects against DNA damage- to keep our skin functioning and looking radiant whilst counteracting photoaging.


IN MORE DETAIL

The skin's immune system is regulated by a vast array and complex balance of different kinds of molecules, proteins, peptides and cells, making sure that it can cope with the many negative influences it is subjected to, such as excessive sun exposure. Aurelia's Repair complex has been specifically designed to support the skin's own protection and repair mechanisms and to counteract premature skin ageing by maintaining a balance within the skin’s immune system.

UV light can induce cellular DNA damage, causing an imbalance in cytokines involved in the skin's immune system and inhibiting repair of damaged DNA. The ability to induce DNA repair is a key quality in maintaining the viability, integrity and functionality of the cells of the skin. Maintaining the cytokine balance is therefore a pre-requisite for counteracting photo ageing and chronic photo damage. The repair complex has been shown to rebalance the proportion of cytokine mediators in the skin, to stimulate DNA repair and counteract UV-induced photo ageing and chronic photo damage. It supports the skin's own protection and repair mechanisms and helps to keep skin cells energetic in order to counteract premature skin ageing.



What is Aurelia’s Peptide Complex?

 

The Aurelia Peptide Complex contains a complex of natural signalling molecules known as cytokines which help to reduce the visible signs of ageing by inducing the production of Extracellular Matrix (ECM) components such as collagen, which enhances the overall structure of the skin. These cytokines are key signalling and regulatory molecules which transfer stimulatory or inhibitory signals to cells, in order to induce a response, resulting in balanced and healthy skin. The network of actives within the Aurelia Peptide Complex is made up of a number of different cytokines, for example the Transforming Growth Factor β (TGF- β), which is one of the most important cytokines in the body.



How does Aurelia’s Peptide Complex work?

 

Aurelia’s Peptide Complex stimulates cells (fibroblasts) that produce extracellular matrix components: collagen (responsible for skin elasticity), hyaluronic acid (responsible for hydration) and fibronectin (responsible for skin support). These components give skin its youthful, supple and toned appearance and their deterioration leads to loss of skin tone, skin sagging and wrinkles.

The Aurelia Peptide Complex delivers an active network of natural signalling molecules, including Transforming Growth Factor β (TGF- β), to stimulate fibroblast activity and restore the composition of the extracellular matrix resulting in firmer skin.

Our scientific studies prove an increase in fibronectin synthesis of 220%, collagen synthesis of 140% and a huge 1,900% increase in natural hyaluronic acid levels. In addition, Aurelia's Peptide Complex has been shown to improve skin smoothness, reduce wrinkle depth and enhance the overall structure of the skin.


IN MORE DETAIL

Fibroblasts are the main connective tissue cells present in the body and work to ensure that the turnover of collagen (responsible for skin elasticity), hyaluronic acid (responsible for hydration) and fibronectin (responsible for skin support) works effectively, so that they can defend against ageing and maintain the Extracellular Matrix. When we become affected by environmental aggressors, inflammation within the skin leads to the degradation of these skin support functions. They begin to work less effectively and this causes our skin to age.

The Aurelia Peptide Complex works to activate the fibroblasts within the skin through a cell-signalling pathway regulated by the network of cytokines within the formulation. By delivering an active form of Transforming Growth Factor β (TGF- β) to the skin, the most important cytokine involved in the process, cell responses are triggered in order to induce fibroblast synthesis and restore physiologically balanced skin. Our scientific studies prove an increase in fibronectin synthesis of 220%, collagen synthesis of 140% and a huge 1,900% increase in natural hyaluronic acid levels. This results in firmer skin and improves elasticity. In addition, Aurelia's Peptide Complex has been shown to improve skin smoothness, reduce wrinkle depth and enhance the overall structure of the skin.



HOW DOES AURELIA’S EYE COMPLEX WORK?

 

Aurelia’s eye complex works on protein complexes within our skin cells (proteasomes) that are key for breaking down unwanted and degraded proteins, for example oxidised proteins that may be present in stressed or aged skin (caused by free radicals).

Although proteasome activity in our skin declines with age, Aurelia’s eye complex can recharge this activity and boost the natural protein recycling process in our skin cells. Our scientific testing showed that skin cells treated with Aurelia’s eye complex have double proteasome activity, compared with untreated cells after just 24 hours.

Our eye complex also boasts a 17-30% visual improvement in the appearance of fine lines


HOW DOES THE AURELIA PIGMENTATION COMPLEX WORK?

 

Aurelia’s Pigmentation Complex significantly reduces the size and colouration of pigmented age spots by up to 61% respectively for brighter and younger looking skin, when used twice daily for 84 days.

Age spots normally appear on our face, neck and hands, these clusters of excess pigment (melanin) are typically the combined result of prolonged sun exposure and high levels of stress in our skin cells.

Our complex is based on Sea Daffodil extract, which balances the production of excess melanin and the way it travels to upper layers of the skin where it clusters and forms dark spots.




How Aurelia helps achieve your skin goals


How do I keep my skin plump?

 

One of the main reasons our skin remains plump and firm is through both the water content of our skin cells and the strength of the collagen structure within our skin. The healthier our collagen structure is and the higher the water content of our skin, the ‘plumper’ our skin cells will be - directly increasing the signs of glowing, firm skin.


IN MORE DETAIL

Fibroblasts are the main cell type found in the dermis. They are responsible for producing the Extracellular Matrix (ECM) and collagen. Together the ECM and collagen form the framework of tissues and play a critical role in skin damage repair. Aurelia Probiotic Skincare's Age Prevention range contains a Peptide Complex which has been specifically designed to induce fibroblast synthesis within the dermis to maintain the skin’s firm and plump structure and protect against such skin damage. Our peptide complex works on the visible signs of skin ageing boosting collagen by 140% and fibronectin by 220% and hyaluronic acid by 1,900%!



Why do we want to boost collagen?

 

Collagen is a protein. Together with elastin, it is responsible for skin strength and elasticity. These proteins give skin its youthful, supple and toned appearance. However, both are susceptible to damage from inflammation and free radicals and, when exposed, can become less effective. For example, healthy collagen fibre molecules 'slide' over one another, which contributes to the soft, supple and resilient properties of younger skin. When damaged, the molecules 'cross link' and become stiff and inflexible which ages the skin dramatically. The collagen strands which help to keep the skin’s structure held together can break and the skin begins to sag forming wrinkles. Damage caused by inflammation and free radical formation also triggers the release of collagen- and elastin-digesting enzymes, which cause their degradation, a key factor in the loss of skin tone, skin sagging and wrinkles. Aurelia’s Peptide Complex increases collagen synthesis by 140%, significantly helping to counteract the signs of premature ageing.



Why is hyaluronic acid important?

 

Hyaluronic acid is a chief component of skin and in particular the Extracellular Matrix (ECM) and is produced via fibroblasts. Its presence enables the ECM to resist compression and it does this by absorbing significant amounts of water. This sits within a matrix in the ECM and keeps water within the skin and improves skin hydration. Hyaluronic acid levels tend to have a direct correlation to skin hydration and are also involved in cellular repair and the regulation of inflammation. As opposed to containing hyaluronic acid as an active ingredient, Aurelia’s Peptide Complex increases the skin’s natural hyaluronic acid levels a whopping 1,900%, resulting in a hydrated and glowing appearance.



How can we help to counteract dullness in ageing skin?

 

Dullness is one of the main concerns of ageing skin and can be one of the first signs that your skin is not optimally balanced. A lack of radiance in the skin causes dullness, and there are immediate steps you can take to counteract it. As our skin ages, the speed at which our cells turnover begins to diminish. It is cell turnover that enables the body to naturally exfoliate, and the slowing down of this process causes a build-up of dead skin cells on the surface which absorb light and cause dullness. The skin’s texture also plays a part in counteracting dullness, which is why it is so important to exfoliate at least twice a week, to reveal smooth, fresh skin. Exfoliators come in a variety of forms, but some of the most effective are naturally derived from plant and fruit enzymes. These enzymes, known as Alpha Hydroxy Acids (AHAs) are found in the Aurelia Probiotic Skincare Refine & Polish Miracle Balm and are Malic and Glycolic acids, which are derived from sugar cane and maple sap. These enzymes dislodge and digest the dead skin cells on the surface of the skin and, when used as a mask, offer effective and noticeable results even after one use. By increasing the rate of cell renewal it promotes smoother, younger looking skin. On contact with water the balm will instantly turn into a milky fluid and on rinsing completely clean, skin is left silky soft, smooth and glowing. The Refine & Polish Miracle Balm also contains very gentle rice bran beads which then help to rinse away the dull dead skin when water is added.

Exfoliation with the Refine & Polish Miracle Balm can be hugely beneficial for all skin types, including congested, acne prone, oily and even dry skins. For congested or acne prone skin, gentle exfoliation is key, as the build-up of dead skin leads to daily impurities settling in pores and causing breakouts or blackheads. Using the Miracle Balm twice a week as a mask will result in smoother skin to the touch, a clearer complexion and a reduction in pore size. The beauty of the Miracle Balm is that it helps to rebalance the sebum levels in your skin, as it does not leave you feeling dry, tight or stripped of oils. As an oil-based texture which emulsifies on contact with water, the Refine & Polish Miracle Balm helps to alleviate the signs of dryness by addressing flakiness and leaving the skin supple. Exfoliation in this way will also increase the effectiveness of subsequent skincare products, as serums and creams can then penetrate beyond the top layer of dead skin, depositing the ingredients and technology where they are most needed.



How do I get rid of dark circles and wrinkles from around my eyes?

 

As we age, the effectiveness of the proteasome within our cells, whose role is to destroy other proteins, slows down significantly, which can lead to the formation of dark circles and wrinkles around the eyes. Strengthening our proteasome improves the natural recycling process in skin cells which helps to delay skin ageing. We therefore we need extra help to improve the appearance of fine lines and wrinkles. Aurelia’s Revitalise & Brighten Eye Dew contains our Eye Complex which is derived from two botanicals: olive leaf extract and jujube to target fine line and wrinkles and results in an age correction improvement of 5 years in just 28 days. The olive leaf extract works to strengthen the proteasome within our cells while the extract of jujube increases the skin’s antioxidant defence system and helps to prevent the cellular decline of proteins.

Along with the three technologies and gorgeous botanicals that feature in the rest of the range, including Omega-rich Baobab, restructuring Mongongo oil and antioxidant-rich Hibiscus, Aurelia Probiotic Skincare has introduced some potent botanicals to the Illuminate & Smooth Puff Reduction Eye Cream to combat the signs of tired, drawn and puffy eyes. Arnica has been incorporated to reduce dark circles, Butcher’s Broom to reduce inflammation and Centella asiatica for its healing and restructuring properties.



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